Altered Prelimbic Cortex Output during Cue-Elicited Drug Seeking
نویسندگان
چکیده
منابع مشابه
Altered prelimbic cortex output during cue-elicited drug seeking.
Cocaine treatment paired with environmental cues establishes a conditioned place preference (CPP) for that environment. After expression of this preference, rats show elevated levels of immediate early genes (IEGs; e.g. c-fos) in the prelimbic cortex (PrL), basolateral amygdala complex (BLC), and nucleus accumbens core (NAcc) compared with drug-unpaired controls. These findings, together with t...
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School of Psychology, University of New South Wales, Sydney, NSW 2052, Australia. Now at: School of Psychology, University of Exeter, Washington Singer Building, Perry Road, Exeter EX4 4QG, UK. Acknowledgements The research reported in this manuscript was supported by a UK MRC Grant (G0701456) held by Lee Hogarth whilst at the University of Nottingham UK. The Author would like to thank Amy Inma...
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Long-term changes in glutamate transmission in the nucleus accumbens core (NAcore) contribute to the reinstatement of drug seeking after extinction of cocaine self-administration. Whether similar adaptations in glutamate transmission occur during heroin and cue-induced reinstatement of heroin seeking is unknown. After 2 weeks of heroin self-administration and 2 weeks of subsequent extinction tr...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2004
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.1685-04.2004